Uterus
Cervix
Cervical intraepithelial neoplasia (CIN)
,or cervical dysplasia, is a medical term that is used to describe
the level of cellular changes in the cervix epithelium, most often
caused by an HPV-infection (contracted through skin to skin
contact). CIN1-3 is used to grade how severe the cellular changes
are and what the risk is that it could develop into a cancerous
lesion.
- CIN1 (low grade SIL):
- CIN2 (high grade SIL):
- CIN3 (high grade SIL):
-
Dysplasia and mitosis in the lower
1/3
of the epithelium
-
Koilocytes:
Cells in the epithelium with perinuclear halo, increased
nuclear size and wrinkled, raisin-like, nucleus with
hyperchromasia.
-
You might see:
-
Binucleated or even multinucleated cells, that tend to be
the same size as the other affected cells.
-
Dyskeratotic cells (cells with keratinization)
-
Dysplasia and mitosis in the lower
2/3
of the epithelium.
-
Dysplasia and mitosis in
3/3
of the epithelium
